Studies on Antiblastic Immunity

Antiblastic Phenomena in Active Acquired Immunity and in Natural Immunity to Pneumococcus

The paper gives the results of a series of experiments made with a special technique for the purpose of testing whether or not so called antiblastic phenomena or bactericidal phenomena play any part in immunity to pneumococcus. The technique employed is that devised by the writer and consists in the isolation of single bacteria and their growth in hanging drops where growth can be continuously ...

Ultrastructural and in Vitro Analysis

©2003 British Editorial Society of Bone and Joint Surgery doi:10.1302/0301-620X.85B5.13588 $2.00 n increased long-term survival of patients with malignant tumours also increases the possibility of the development of skeletal metastases and pathological fractures. The management of bone metastases includes the removal of gross disease and the administration of local adjuvants. We have investigat...

Animal Models in Studies of Cardiotoxicity Side Effects from Antiblastic Drugs in Patients and Occupational Exposed Workers

Cardiotoxicity is an important side effect of cytotoxic drugs and may be a risk factor of long-term morbidity for both patients during therapy and also for staff exposed during the phases of manipulation of antiblastic drugs. The mechanism of cardiotoxicity studied in vitro and in vivo essentially concerns the formation of free radicals leading to oxidative stress, with apoptosis of cardiac cel...

Drug–Drug Interactions Based on Pharmacogenetic Profile between Highly Active Antiretroviral Therapy and Antiblastic Chemotherapy in Cancer Patients with HIV Infection

The introduction of Highly Active Antiretroviral Therapy (HAART) into clinical practice has dramatically changed the natural approach of HIV-related cancers. Several studies have shown that intensive antiblastic chemotherapy (AC) is feasible in HIV-infected patients with cancer, and that the outcome is similar to that of HIV-negative patients receiving the same AC regimens. However, the concomi...

Studies on the Duration of Immunity conferred by a Live Modified Sheep Pox Tissue Culture Virus Vaccine